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Biochemical tests can also identify tendinopathy by identifying the regulation of matrix metalloproteinases and their inhibitors.
Rab geranylgeranyl transferase blockade with 3-PEHPC reversed the depletion of Drp1, accumulation of mitochondria, ANA production and nephritis in lupus-prone mice, identifying the regulation of mitochondrial homeostasis by HRES-1/Rab4 as a mechanism of pathogenesis and potential target for treatment in SLE.
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In this study, we have characterized and investigated the mechanism of action of a number of reported HIF inhibitors and identified the regulation of HIF-1α protein synthesis as an important target of several HIF-inhibitory compounds.
The present study not only provides a better understanding of the HIF-1α signaling pathway, but also identifies the regulation of HIF-1α protein synthesis as an important target of HIF-1α-inhibitory compounds.
Specialists identified the regulation of patient flow as one of the primary aims for collaborative care.
These experiments identify the regulation of both OCT6 and KROX20 by cyclic AMP as abnormal in Merlin-null schwannoma cells.
We observe from the results that our approach correctly identifies the regulation of SWI4-SWI6 and MBP1-SWI6 complex by the CLN3-CDC28 complex.
Although most of the biochemical steps involved in lipid biosynthesis are known and the key genes have been identified, the regulation of the processes that results in the final oil composition and total amount is not understood.
Global gene/protein expression studies for hypoxia are widely used to identify the regulation of various genes and proteins, and a large amount of global molecular data for hypoxia has been published and accumulated over time.
Investigations in melanoma tumor cells that can interconvert their mode of protrusion formation, allowing them to migrate through different types of environments, have identified the regulation of contractility and actin protrusivity as central for the plasticity in the mode of cell migration [ 51 ].
Parallel comparison of PTMs occurring in complex biological processes is useful in identifying the differential regulation of PTMs.
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