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My research aims toward designing and engineering a novel system to study the mechanism of action of B7-H4 withopeses of identifying the receptor and introducing a novel target to the field of immunotherapy.
Lastly, we pursued experiments aimed at identifying the receptor(s) through which Sema3C exerts its functions on endothelial cells.
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While at Yale, Dr. Greengard made seminal discoveries that have shaped the face of modern neuroscience, identifying the receptors for the neurotransmitter dopamine and discovering key cellular signaling pathways that regulate neuroplasticity, explaining basic mechanisms of learning and memory.
A high correlation would identify the receptor in question.
Next, we sought to identify the receptor through which FLP-7 acts.
Previous studies on rats identified the receptor in the brain on which ketamine acts, and showed that blocking this receptor reduces background activity in the brain.
Therefore, we aimed to identify the receptor of Cry8Da toxin in adult P. japonica BBMV.
In this study, we sought to identify the receptor that mediates transduction by AAV-GMN.
RESULTS: Automated analysis of images from this RNA interference screen identified the receptor tyrosine kinase Pvr, Ras pathway components and several novel genes as regulators of cell size.
We identified the receptor tyrosine kinase (RTK) Insulin-like receptor (InR) as a major Pvr Enhancer, and the nuclear hormone receptors Ecdysone receptor (EcR) and ultraspiracle (usp), corresponding to mammalian Retinoid X Receptor (RXR), as Pvr Suppressors.
But the real breakthrough in understanding chilli burn came in 1997, when pharmacologist David Julius and his colleagues at the University of California, San Francisco, finally identified the receptor for capsaicin, the active ingredient in chilli heat.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com