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The power of IHC lies in its capacity to localize antigens within tissue samples, thereby identifying the cell types and subcellular compartments in which antigens are located.
In addition to the electrophysiological experiments, the whole-cell configuration of the patch-clamp technique has been used to fill cells with fluorescent dyes (especially Lucifer-Yellow), thereby identifying the cell under investigation.
Based on the results in Figure 4(b), the intensity threshold for identifying the cell outline was determined to be 55. Figure 4 (a) Contours of the fluorescence intensity at the cell bottom (right image in Figure 3(b)).
This debate could be clarified by identifying the cell(s) of origin of a mouse model for MFH.
A fundamental problem in cancer research is identifying the cell type that is capable of sustaining neoplastic growth.
A fundamental problem in cancer research is identifying the cell type that is capable of sustaining neoplastic growth and its origin from normal tissue cells.
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Previous attempts at Rosi may have failed because of difficulty identifying the cells and incomplete activation of recipient eggs, the study authors said.
New emerging cell and animal models are of great importance for identifying the cell-of-origin for retinoblastoma and for mapping of the early events in tumorigenesis.
Identifying the cell-of-origin, studying the developmental programs and cellular context, may help us to understand why certain cells undergo neoplastic transformation as a result of RB1 inactivation.
Our work extends these findings by identifying the cell-types that undergo a canonical response to transgene expression.
Considering that epigenetic modifications, enzymes, and non-coding RNAs are often cell type specific makes these cellular elements prime targets for identifying the cell-of-origin.
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