Taken together, our study identifies Evi/Wls as an essential regulator of glioma tumourigenesis, identifying a pathway-specific protein trafficking factor as an oncogene and offering novel therapeutic options to interfere with the aberrant regulation of growth factors at the site of production.
To date, we have not identified a pathway whereby Bt or herbicide-resistant maize, for example, displaces genetic diversity any more than typical hybrids.
"The C4A paper is one of the most important papers in schizophrenia in our times, because it identifies a pathway and provides a mechanism," Lieberman said.
The LINCS database was used to identify a pathway targeted by the agents that improved function of PAH cells.
The control of HIV latency by mTOR signaling identifies a pathway that may have significant therapeutic opportunities.
Burkitt Wright, E.M. et al. Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance.
Alice Park reports for TIME that researchers from MIT and Harvard have identified a pathway that controls how much fat cells burn or store.
Using real-time microscopy and sophisticated analytical tools, coupled with genetics and molecular genetics, we have identified a pathway in budding yeast in which proteins are recruited to endocytic sites in a highly regular, sequential manner.
Finally, we characterize the kinetics of several NO surface reactions and identify a pathway that may contribute to the decomposition of NO to N2 and N2O over partially reduced surfaces.
They identify a pathway triggered by ROS and mediated by the Rho effector ROCK and its substrates that influences tissue patterning and homeostasis through the coordinate regulation of both mitochondrial morphology and tissue tension.
