Sentence examples for identifying a linkage from inspiring English sources

To confirm these results, we also tested Mut, a marker that is closely linked to Col9a1 on Rattus Chr 9. Mut is located 7.13 Mb from Col9a1 on Rattus Chr 9 but in Mus is located separately on Chr 17. Mut did not link to Col3a1 but did co-segregate with Col9a1 (LO D= 12.0), thus identifying a linkage similarity between the Rattus and deer mouse genomes.

Multipoint non-parametric analysis identified a linkage peak with a LOD score of 2.31 at 103.5 cM (where alpha power in our study had a LOD score of 2.2) [48].

This linkage was rapidly replicated by Rihet et al. [24] in Burkina Faso (marker D5S658) while Flori et al. [18] identified a linkage at the same marker D5S636 in a second population in Burkina Faso and an association with one marker (D5S487) within the 5q33.3 region.

Genome-wide linkage analyses were performed on four clinical and parasitological phenotypes and association analyses using the family based association tests (FBAT) method were carried out in regions previously linked to malaria phenotypes in literature and in the regions for which we identified a linkage peak.

Previous studies have identified a linkage between the expression of β1 and αv integrins and breast cancer [ 4, 6].

We previously identified a linkage locus for DSAP on chromosome 16q24.1-24.3 in a four-generation Chinese DSAP family (Luan et al., 2011).

One of the first successes in type 2 diabetes genetic research was a study conducted in Icelanders that identified a linkage peak on chromosome arm 5q (4).

Not surprisingly, SNP analysis also identified a linkage signal in the 11q13.5 region for the family RUL153 that was noted in Smith et al. [ 16].

A study of identical twins indicated hereditary factors are of prime importance in CDH [ 10], and a genome-wide screening of a Japanese family with acetabular dysplasia identified a linkage on a limited location of the specific chromosome [ 11].

Here, we performed a genome-wide linkage scan in a unique three-generation family with an autosomal dominant EDS-HT phenotype and identified a linkage interval on chromosome 8p22-8p21.1, with a maximum two-point LOD score of 4.73.

Recently, a genome-wide screening of one 18-member, multigeneration family with DDH identified a linkage on a limited location of the specific chromosome 17q21 where HOXB9 gene located in [ 20].