Sentence examples for identifying a functional from inspiring English sources

Using molecular biology approaches, we demonstrate that ectopic expression of META1 and site-directed mutagenesis of selected residues in the predicted META1 cavity do affect secretory processes in Leishmania, thus establishing a function for this poorly characterized protein as well as identifying a functional domain within the molecule.

We propose the findings presented here provide important beacons identifying a functional pathway [3] likely to be disturbed through different mechanisms in relation to therapy resistance in advanced disease.

This is illustrated by the non-sequential sequence alignment of the PrgI and Bcl-xL ligand binding sites in Figure 2. The exclusion of the sequence connectivity as a constraint to determine an alignment illustrates the advantage of CPASS in identifying a functional relationship and the limitation of global sequence and structure alignments such as Dali and BLAST [29], [30].

That might be a more sensitive means of identifying a functional enrichment for the duplicated regions.

hCAP18/LL-37 hCAP18/LL-37regulin-induced mitogen-amplified protein kinase (MAPK) signalling through ErbB2, identifying a functional association between Heregulin-inducedErbB2 in breast cancer.

We were interested in identifying a functional end point that is relevant to the in vivo situation and susceptible to disturbance by chemicals.

Also, prior reviews of anterior pituitary function in SIOD patients have not identified a functional pituitary defect [ 3].

Integrated genomics identified a functional interaction between CLEC12A and an E3-ubiquitin ligase complex that functions in antibacterial autophagy.

Neri, F. et al. Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells.

These parallel structure function characteristics identify a functional, allosteric site on the surface of this enzyme.

Experimental data have identified a functional 5-HT system in bone, although its role is unclear.