More importantly, these studies identified unexpectedly a non-phosphorylated vectorized peptide P2a, as another potent inhibitor of STAT3 biological activity and thus give further insight for the development of novel inhibitors.
Among them, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was identified unexpectedly as one of the up-regulated proteins.
The six women who had died post-partum were identified unexpectedly and included because of the rarity of available data.
The DXO activities were first identified, unexpectedly, from studies on yeast Rai1, the protein partner of the nuclear 5′ 3′ exoribonuclease Rat1.
In the present study, we have identified unexpectedly potent effects of a ubiquitously used chemical, BADGE, on adipogenesis in MSCs at nanomolar levels.
By targeting the extension we identified, not unexpectedly, analogs mimicking nsDSK II, yet, surprisingly, we also discovered novel agonists with increased (super) and opposite (protean) effects.
Pseudo-transition analysis recapitulates known biology and identifies an unexpectedly sparse, transition-dependent regulatory landscape: typically a handful of regulatory events drive adaptation between carbon sources, with transcription mainly regulating TCA cycle flux and reactants regulating EMP pathway flux.
We have also identified an unexpectedly large number of genes whose specific expression in late conjugation indicates that, in addition to DNA elimination, chromosome fragmentation and rDNA amplification, a number of heretofore unrecognized developmental processes occur specifically during late conjugation.
X-ray crystallographic and biochemical analyses have identified an unexpectedly large variety of activation mechanisms.
Reubi and Waser identified an unexpectedly high incidence (>90%) of CCK2 receptors in medullary thyroid carcinomas (MTC), whereas differentiated thyroid cancers do not express CCK2 receptors [ 10].
