Detection of genome-wide DNA polymorphisms by high-throughput sequencer enabled to identify sequence diversity derived from anther culturing and genomic locations of heritable traits.
Here, we used computational design to identify sequence features that determine the degree of helix axial rotation in four-helical homo-oligomeric antiparallel coiled coils.
Calculations are performed for a variety of similar backbone structures to identify sequence properties that are robust with respect to minor changes in main-chain structure.
Here, we tested whether MD simulations could be used as a post-design screening tool to identify sequence mutations leading to domain-swapped dimers.
The aim was to design a high-throughput genetic analysis based on denaturing high-performance liquid chromatography to identify sequence variations in the gene coding for Protein S.
A semiautomated analysis pipeline was used to identify sequence variants [14].
EvoPrinterHD also includes algorithms that identify sequence rearrangements in the aligning regions of the test genomes.
Gene scanning software was used to identify sequence variation by melt profiling.
The program then carries out preclustering and performs the all-against-all megablast to identify sequence pairs for NW alignment.
All aligned nucleotide sites, including the insertions/deletions, were used to identify sequence polymorphisms at each of the four loci.
sRNA_Annotate searches the output of this IGR vs. IGR BLAST to identify sequence alignments that overlap the RNA-encoding genes in both the query and database IGR sequences.
