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The method to identify prototype samples representing the subtypes has been previously described [ 3].
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Recently, Capellari and De Stefano (2013, 2014), in a case study on university-owned and university-invented patents of two Italian universities, identified prototypes of different relational mechanisms of knowledge diffusion through patenting, embedding different rationales for the attribution of property rights.
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About UNICEF Innovation UNICEF Innovation is an interdisciplinary team of individuals around the world tasked with identifying, prototyping, and scaling technologies and practices that strengthen UNICEF's work.
The study followed an iterative pattern where issues of importance are identified, prototypes are developed and refined, and the results are evaluated for utility (see Figure 1).
UNICEF Innovation is an interdisciplinary team of individuals around the world tasked with identifying, prototyping, and scaling technologies and practices that strengthen UNICEF's work to improve children's lives around the world.
For more information about UNICEF and its work visit: www.unicef.org About UNICEF Innovation: UNICEF Innovation is an interdisciplinary team of individuals around the world tasked with identifying, prototyping, and scaling technologies and practices that strengthen UNICEF's work to improve children's lives around the world.
For more information about UNICEF and its work visit: www.unicef.org Follow us on Twitter and Facebook About UNICEF Innovation UNICEF Innovation is an interdisciplinary team of individuals around the world tasked with identifying, prototyping, and scaling technologies and practices that strengthen UNICEF's work to improve children's lives around the world.
In fact, it has been observed by Bornberg-Bauer in simulations of neutral protein evolution that one can identify a prototype sequence that is maximally stable both thermodynamically and mutationally [ 21, 22].
Examples of some of the markers used to identify each prototype include a Basal-Like cluster with highly expressed cytokeratin (KRT 5, 14, 17) and cell proliferation genes and low expression in genes associated with estrogen responsiveness and ERBB2.
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