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High-throughput sequencing has the ability to identify modest or even low abundant miRNAs exhibiting expression differences between distinct samples, to an extent that previously could not be effectively detected.
However, current methods for analyzing allelic RNA expression from RNA-Seq have substantial drawbacks when attempting to reliably identify modest allelic differences (<2.5-fold).
The quality of exposure assessment has a large impact on the ability of an epidemiological study to identify modest increased RRs.
These authors identify modest levels of social capital among this population group, although relatively better mental health is also detected (17).
It could therefore be argued that our pathway-linked gene approach to identify modest risk loci, in combination with large scale GWAS, may be appropriate to ensure complete coverage of potential prostate cancer risk factors.
While the results for the remaining traits did not indicate strong inherited variation, it is important to underline that sample sizes were too small to identify modest or low levels of inherited phenotypic variation.
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Four studies in recent years identified modest declines, but a new one that looks separately at Americans lacking a high school diploma found disturbingly sharp drops in life expectancy for whites in this group.
Four case control studies identified modest and inconsistent associations.
We identified modest improvement in glycemic control over time.
We identified modest effects of BMP4 variants on the risk of type 2 diabetes.
Overall, meta-analyses identified modest effects for single interventions on two review outcomes.
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