Sentence examples for identify impurity from inspiring English sources
Understanding cefpodoxime proxetil fragmentation pathways can help identify impurity structures.
In ToF-SIMS measurements we could indeed identify impurity elements such as Si and Ca at TPBs of strongly polarized high temperature deposited [25] Pt electrodes – cf. Fig. 15.
However, its application to identify impurities of these frequently used drugs is not sufficient at present.
This systematic study to identify impurities in cefpodoxime proxetil samples will assist us to improve its quality and safety.
The MB method is commonly used to assess sample purity and is generally applied as HPLC with mass spectrometry (MS) to identify impurities.
The aim of this study was to identify impurities observed during the stability tests of a new liposomal dosage form of azelaic acid that is composed of phosphatidylcholine and a mixture of ethyl alcohol and water using HPLC-ELSD, gas chromatography flame ionization detection (GC-FID), and GC-MS methods.
In each case the relative standard deviations (RSD) of the peak area of an identified impurity peak, normalized to the sum of the area of the "target impurities" suggested in the CHAMP profiling method, was assessed.
Among the potential problems they found was a failure to properly follow the steps for identifying impurities and deficiencies related to manufacturing equipment.
This guideline provides assessment on potential impurities such as starting materials, reagents and intermediates downstream of the starting material, in addition to other identified impurities.
Among all initially identified impurities, the key impurities, having the biggest impact on the product purity in the reactive distillation process, are found.
Based on the results, degradation pathway for the drug has been proposed and synthesis of identified impurities i.e. impurities (Impurity-I (1), Impurity-III (3), Impurity-V (5) and Impurity-VIII (9)) are discussed in detail to ensure in-depth understanding of OMP and its related impurities and optimum performance during lifetime of the product.
