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The potential application of this approach is to identify efficacy markers for monitoring different OA treatments.
Second, we sought to identify efficacy biomarkers for anti-IL-23 therapy in CD using the same animal model.
As biomarkers of disease state and treatment efficacy are becoming increasingly important in drug development, we sought to identify efficacy biomarkers for anti-IL-23 therapy in Crohn's disease (CD).
Excluding from the trials eyes/patients that show little disease activity and are not expected to progress during the trial period would offer a better chance for development of VTDR in the placebo control eyes, thus creating the conditions to identify efficacy of the drug being tested.
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We identified efficacy clinical trials enrolling patients with cerebrovascular diseases between 1980 and 2008 using an electronic database.
Additionally, key animal studies involving procedures both intra-abdominally and elsewhere throughout the body have been summarized, identifying efficacy and safety at these diverse locations.
Markov-model-based cost-effectiveness analysis, informed by systematic reviews, which identified efficacy, utilities and adherence data inputs.
Regarding the combination test we present results for testing the intersection hypothesis as well as for identifying efficacy in at least one population.
A previous report also identified efficacy for DES in a smaller group of 11 patients, in whom all but one had received at least two prior therapies and four achieved a complete response or a partial response [ 6].
Sensitivity analyses explored the effects of varied key parameters such as vaccine cost (to help establish price points), vaccine efficacy (to identify vaccine efficacy targets), and risk of infection (to evaluate different target populations).
The purpose of study was to identify the efficacy of real-time dual examination of two different modalities for the evaluation of vocal fold vibration in human subjects and vocal fold vibration simulator.
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