Sentence examples for identify downstream from inspiring English sources

Using mechanistic Bayesian networks to identify downstream targets of the Sonic Hedgehog pathway.

A kinase screen was undertaken to identify downstream targets in the V600EB-RAF signaling cascade.

This study was designed to evaluate effects of specific p38 MAP kinase inhibition on gene and protein expression of essential hematopoietic cytokines in primary human bone marrow stromal cells (HBMSC) and to identify downstream transcription factors (TF) regulated by the p38 MAP kinase signalling pathway.

d Experimental procedure to identify downstream metabolic pathway and regulatory elements of DXR through microarray comparison of dxr mutant vs wild type.

Using these new tools, we aim to identify downstream cellular signaling pathway and events that mediate the tumorigenic roles of MLL2/MLL3 deficiency, and illuminate the roles of MLL2 in different cellular contexts.

To identify downstream signaling molecules through which intraocular pressure (IOP) is lowered following treatment with the prostaglandin analog latanoprost.Total RNA and protein isolated from primary human Schlemm's canal cells (n = 3) treated with latanoprost (free acid; 100 nM) were processed for quantitative PCR and Western blot analysis.

A first step to understand the function of Oct3/4 is to identify downstream target genes.

One aim of our study was to identify downstream binding partners of the Src kinase SmTK3.

A complimentary approach is to identify downstream genes that are tightly correlated with fluctuation of miRNA expression.

To identify downstream targets for Cullin3 in neurons, we tested several Drosophila BTB domain proteins, including the actin crosslinking BTB-domain protein Kelch.

We used a two-step strategy to identify downstream target genes and signaling pathways affected by PIK3CA mutations in breast tumors.