Exact(4)
Since EEM assumes that module genes, i.e., genes belonging to the same expression module, behave similarly across all samples, EEM potentially fails to identify an expression module whose module genes exhibit coherent expression patterns over only a subset of samples, i.e., sample subgroup-specific expression module.
In the present study, we used total RNA in oligo dT primed cDNA reactions to identify an expression phenotype associated with the MFS genotype in cultured skin fibroblasts.
To identify an expression profile that distinguishes human RPE from other cell types, we compared the expression of native adult and fetal RPE and primary cultures of fetal RPE against 78 different human tissues and cell cultures (26).
Application of the autoimmunity array to blood samples allowed us to identify an expression pattern specific to Takayasu arteritis based on the Spearman rank correlation by comparing the reference profile with those of several autoimmune diseases and healthy volunteers (HVs).
Similar(56)
We identified an expression signature of genes that were specifically expressed by bronchial epithelial cells and keratinocytes.
Because a dominant negative effect of the expression of this protein on influenza infection has been reported [13], we carefully identified an expression level of PH-GFP that would avoid inhibition of infection (Figure S3A, B).
Global gene expression analyses of human breast tumors have identified an expression pattern consistent with up-regulation of the canonical Wnt/β-catenin pathway that associates with the basal-like tumor subclass [54], [55].
In a similar fashion as reported above, we identified an expression index of β-tubulin associated transcripts.
It is, however, noteworthy that Loi and colleagues [ 18] identified an expression signature derived from exon 20 PIK3CA-mutated tumors.
In rice, a global-scale microarray expression analysis identified an expression pattern for all Type II and Type I MADS-box genes during vegetative and reproductive development [ 9].
By utilising gene expression array data published by Li et al (2009), we identified an expression signature linked to WNT/ β-catenin pathway activation.
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