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When Dante meets Virgil in the first canto of the Inferno, he identifies the classical poet with the material book through which he came to know him, which he calls a "volume" [volume].
In the case of STAT1, it is clear that our approach correctly identifies the classical GAS motif TTC[TC]N[GA]GAA as the main binding motif [6].
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We can see that both methods are able to identify the classical GAS motif.
Here, we identify the classical type II cadherin-9 as a specific and reliable marker molecule for renal fibroblasts.
The correlation of activation differences between numbed and non-numbed stimuli with the pain ratings basically identified the "classical" network detected in studies on empathy for pain.
In summary, the partial least squares regression and the principal component regression are able to identify the classical GAS motif for STAT1 and the initiator site and the downstream promoter element for RNA Polymerase II.
As we can see, all regression methods demonstrate similar performance and are able to identify the classical GAS motif for STAT1 and the initiator site and the downstream promoter element for RNA Polymerase II.
Four different PDGF chains have been identified, the classical PDGF-A and PDGF-B and the more recent PDGF-C and PDGF-D isoforms.
Two families of histone deacetylases (HDACs) have been identified: the classical HDAC family and the NAD + -dependent, the so-called SIR2 family (sometimes called class III HDACs).
Interestingly, within these pathways, significantly affected sub-pathways/sub-complexes could be identified: the classical TGF-β sub-pathway, the classical and the c-jun kinase (JNK /p38 MAPK sub-pathway(s), and the sub-complex of anti-apoptosis.
While previous studies have identified the classical ER in only a small percentage of human melanomas via immunohistochemistry [ 30], the low affinity type II ER has been characterized in a variety of human melanomas [ 31].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com