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Liarski, V.M. et al. Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue.
Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, et al. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma.
This article identifies functional changes in the DLPFC during a working-memory task in medication-free schizophrenia patients, positing a region-specific localization of schizophrenia pathophysiology.
Thus, this study identifies functional elements in MCPH1 and MDC1 BRCT domains potentially involved in cell cycle regulation and shows that they correspond to equivalent residues in the BRCA1 BRCT domains.
Given these caveats, the algorithm presented here identifies functional CREs with considerable reliability when applied to the genomic region around photoreceptor-enriched genes.
We found that most of the gene sets had statistically significant literature cohesion, indicating that our method correctly identifies functional coherence of gene sets.
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Regarding applications, identifying functional MREs is critical to determining the biological function of microRNAs.
The electrodes are stimulated to identify functional areas of the brain to be avoided in surgery.
These associations give strong support to the notion that we are able to identify functional elements altered by genetic variation.
In addition, FTIR was used to identify functional groups formed in the AAP.
Possible mechanisms explaining the formation of identified functional groups were discussed.
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