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Compared to a competing pathway activity inference approach called SPIA, our method identifies altered activities in cancer-related pathways with fewer false-positives.
Compared with a competing pathway activity inference approach called SPIA, our method identifies altered activities in cancer-related pathways with fewer false-positives in both a glioblastoma multiform (GBM) and a breast cancer dataset.
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Curto et al., also identified altered kynurenine pathway metabolites in serum of chronic migraine patients [89].
(2) identify altered signaling pathways of neonatal lung injury, and test novel treatment strategies.
These experiments failed to identify altered expression in wounded limbs compared with controls.
Can we identify altered signaling pathways in PKD that can successfully be modified by pharmacological interference in patients?
The results presented identify altered material properties and improved cellular interaction on Ti30Ta nanotubes as compared to Ti30 Ta alloy.
To identify altered gene expression, the averages of biological duplicates were compared, and fold changes in gene expression ≥2 were considered significant.
We have previously identified altered epigenetic patterns at a gene enhancer of the diacylglycerol kinase alpha (DGKA) locus in normal skin fibroblasts derived from fibrosis patients.
In this study, we identify altered cognitive processing of tactile stimuli in CRPS patients that we propose marks heterogeneity in tactile decision-making mechanisms.
A multi-marker panel containing 6 of the identified altered genes (ENO1, FHIT, HYAL2, SKP2, CDKN2A, and 14-3-3zeta 14-3-3zeta 14-3-3zetantiate betwere pablento with NSCLC andifferentiateh 86.7 % specificity and 93.9 % sensitivity [63].
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