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Figure 7a shows an example (PDB ID: 4MSW) where the predicted low TM-distance (0.4) identifies a template close to the native conformation of the target loop, leading to a high-quality H3 model (RMSD = 0.3 Å).
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This confirms that the scramblase family is related to the DUF567 family and therefore identifies a structural template for modeling of the scramblases.
Our experimental and theoretical results permitted us to identify a topographical template which may provide a guide for the design of new peptides with antifungal effects.
Our experimental and theoretical results have led us to identify a topographical template which may provide a guide for the design of new nitrosopyrimidines with antifungal effects.
The experimental and theoretical results allow us to identify a topographical template which may provide a guide for the design of new compounds with antifungal characteristics against C. neoformans.
Nevertheless, standard bioinformatic approaches fail to clearly identify a suitable template for molecular modeling.
In this paper, we identify a stable template of Pb bilayer on Cu(111) surface with a periodic nanometer structure and reveal the atomic and electronic structure properties of the template.
The conformation of a loop can be predicted by identifying a loop template from homologous structure or by searches in databases of loop conformations of various lengths obtained from known three-dimensional structures [59], [66] [68].
It first identifies a set of invariant templates by inspecting the lifted representation of the domain and then checks these templates against properties that assure invariance.
In phase-one of the proposed model, the Constraints Optimisation Engine identifies a subset of suitable resource templates which meet all of the hard constraints.
Each vCell is identified by a template which is used by the manager to create components, allocate resources, reconfigure existing components, and achieve all interactions with the underlying infrastructure and with other vCells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com