Sentence examples for identified variant in from inspiring English sources

In practice it should be noted that the actual effect of the identified variant in an initial study is usually overestimated, a phenomenon called winner's curse [4] [6].

The identified variant in the MMP12 promoter mediates decreased promoter activity by diminishing AP-1 binding, which leads to decreased MMP12 expression (Wu et al, 2003).

Most of the ESBL enzymes are of CTX-M types, with CTX-M-15 being the most frequently identified variant in particularly in France [ 3].

For example, if the disorder affects the cerebral cortex but the gene product is only active in the tissues located in the foot, then one cannot make a good argument about the identified variant in the respective gene as being "causal".

We identified variants in the CC domain with intermediate effects in transcription that correlate with failure to interact with the PALB2 protein (Figure 3).

We identified variants in CVID disease genes TNFRSF13B, TNFRSF13C, LRBA and NLRP12 and enrichment of variants in known and novel disease pathways.

Previous studies have identified variants in the gene for GluA receptors in persons with migraine [28].

Other identified variants in MYOC and OPTN have been previously described and do not seem to contribute to POAG risk.

Recent genome-wide association studies of Alzheimer's disease (AD) have identified variants in BIN1, CLU, CR1 and PICALM that show replicable association with risk for disease.

All individuals carried the newly identified variants in the heterozygous state.

We identified variants in several genes as conferring disease risk for both men and women jointly, while other variants showed evidence for a gender-specific effect.