Exact(7)
We identified trial registration numbers for 35 of the 45 included trials.
In stage 1 we assessed the reliability and completeness of the identified trial data.
All nations with no identified trial output had GDPs that predicted zero trial activity.
We identified trial participants with moderate vitamin B-12 status by using standard clinical testing procedures (serum vitamin B-12 concentration) (3).
We ascertained in ClinicalTrials.gov whether each identified trial from the FDA approval packages of each drug (the 'all trials' study sample) was registered and reported results.
One identified trial of glipizide added on to human proinsulin [ 15] was not included in the systematic review because human proinsulin is not a recognised diabetes treatment despite meeting all other inclusion criteria.
Similar(53)
References of all identified trials were also inspected for more studies.
Furthermore, all references lists in identified trials were scrutinized for studies not indexed in the electronic databases.
A systematic review first identified trials on head-louse infestation; 49 were selected and their methodological constraints assessed.
Further trials were identified by hand searching the reference lists of identified trials and review articles, relevant NICE guidelines and Health Technology Assessment reports.
Figure 1 shows how we identified trials.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com