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A synthetic 22-mer peptide corresponding to the carboxy-terminal amino acid residues 361 382 of p53 was the first compound identified to restore mutant p53 activity in tumor cells thereby inducing apoptosis (Selivanova et al., 1997).
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Lastly, the lineage specifiers depicted as pluripotency rivals, such as GATA3 and PAX6, have been identified to be able to restore pluripotency in somatic cells.
Unfolded protein response (UPR), the major ER stress pathway, is identified essentially to restore ER homeostasis to promote cell survival.
In our study we identified ribavirin to restore ESR1 gene re-expression alone and even more in combination with suberoylanilide hydroxamic acid (SAHA - up to 276 fold induction).
"The challenge now," he said, "is to identify ways to restore plastic and glass recycling in a more cost-effective fashion".
"This hearing will help us identify ways to restore market confidence for farmers, ranchers and investors through improved regulatory oversight and strengthened protections for customer accounts".
David Quam, NGA federal relations director, told HuffPost that the group plans to work with Congress to identify ways to restore the Air National Guard funding.
These studies highlight the potential therapeutic value of identifying ways to restore a 'healthy' microbiota, a process we will refer to as rebiosis.
To evaluate the ability of identified Rf genes to restore the fertility of BT-type CMS lines, we crossed NIPA with the CSSLs carrying various Rf genes.
In a statement, Toyota said it was "carefully monitoring the situation in each region and for each vehicle model and is every day working its hardest to identify every way to restore production as much as possible" but that in the meantime, "reduced production levels may have a significant impact" on its financial results.
When the mismatch becomes too large, control performance suffers and it becomes necessary to re-identify the plant to restore performance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com