Sentence examples for identified to date with from inspiring English sources

Only few pharmacological inhibitors of HSP70 have been identified to date, with most of them lacking specificity or properties necessary for clinical use.

Alpha-satellite DNA is the only centromeric DNA sequence identified to date with a proposed role in kinetochore formation and maintenance.

In excess of 60 HIF target genes have been identified to date, with gene expression profiling confirming significant overlap between HIF-1 and HIF-2 regulated genes.

Figure 3 displays the sizes of various DISC1 species identified to date, with the predicted molecular weights of proteins derived from known transcripts shown for comparison.

Finally, in bovine, although the genome is completely sequenced, only four sub-families were identified to date, with SERPINA1, SERPINA3 and SERPINA5 assigned to chromosome 21 and SERPINA7 probably on chromosome X as all other mammal SERPINA7s.

Over 50 members have been identified to date, with several displaying potent antimicrobial activity at nanomolar levels against nosocomial pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and oxacillin-resistant Gram-positives (2, 3).

Of the 24 gene clusters that have been identified to date, together with their corresponding products (Supplementary Table S1), 21 gene clusters were successfully detected with the optimized parameters described above (Table  1).

These findings support the mounting evidence that different genetic loci are associated with autoantibody-positive and autoantibody-negative RA, possibly suggesting that many of the genes identified to date are associated with autoantibody production.

Klee et al. [ 18] indicated that all of the apocarotenoid volatile QTLs identified to date are associated with carotenoid biosynthetic enzymes, and substrate availability rather than enzyme synthesis appears to be limiting apocarotenoid volatiles.

Among the various outcome parameters identified to date in patients with septic shock, time to administration of appropriate antimicrobial treatment has been documented to be the factor most predictive of outcome, with survival probability dropping from 83%to8 8% with an antibiotic delay of 24 hours.

Mutations in at least seven genes have been identified to date as causing MODY, with HNF1A, HNF4A and GCK accounting for approximately 94% of cases [ 3].