Sentence examples for identified to be downregulated from inspiring English sources

Lama3 has been identified to be downregulated within human AAA biopsies [ 9].

MiR-22 was identified to be downregulated in diverse cancers, including colon cancer, hepatocellular carcinoma, ovarian cancer, lung cancer, prostate cancer and esophageal squamous cell carcinoma (ESCC).

Interestingly, miR-126 was also identified to be downregulated in atherosclerotic coronary artery disease [ 119], one of the major cardiovascular complication in diabetic individuals.

Alternatively, ASCL2, identified to be downregulated upon KIAA1199 knockdown, may promote progression through the G2/M cell-cycle checkpoint and may be a putative regulator of proliferation overexpressed in intestinal neoplasia (Jubb et al, 2006).

Using miRdeep2, an algorithmic software, four distinct miRNAs miR-181a-5p miR-181a-5p miR-181a-5p3p, and miR-218-5p) were identified to be downregulated with a subsequent decrease in MDR [ 84].

In fact, let-7a, let-7c, and let-7e belong to the let-7/98/4458/4500 miRNA family and miR-125a belongs to the miR-125a-5p/125b-5p/351/670/4319 miRNA family, both of which we identified to be downregulated by β4 in two of the three arrays (Table 2).

MiR-3656 was the most downregulated one in our study which had been identified to be significantly downregulated in colorectal carcinogenesis only in one literature [ 40].

In addition, a total of 60 signaling pathways have been identified to be either upregulated or downregulated in these cell types.

Of the 849 enhancer-like lncRNAs (Table S6) that were detected by the GENCODE annotation, 15 were identified to be upregulated and 9 as downregulated lncRNAs.

Using the criterion of < 5% FDR, 241 transcripts were identified to be significantly up-regulated or downregulated by genotype and/or ACTH challenge (see additional file 1).

To confirm the differential expression of genes revealed by RNA-Seq, 12 genes identified to be co-upregulated and 8 genes identified to be co-downregulated in TO-VS-IFN and TO-VS-SAV3 were randomly chosen for qRT-PCR validation.