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In 1993, SOD1 was the first protein to be identified to aggregate in FALS cases carrying a mutation in the SOD1 gene [ 167].
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Also, the proper utility function and merging rules are identified to achieve the aggregate utility which can reflect comprehensive qualities of HESSs.
The proteins identified to be present in ALS aggregates play a role in a wide range of cellular processes with a marked overlapping role for TDP-43, FUS and ATXN2 in RNA metabolism and for OPTN, UBQLN2 and VCP in protein quality control and degradation (Fig. 2).
Policy-makers have not always found it easy to identify their needs or to aggregate the demands from various sources [ 7].
The mutants we identify here as slow to aggregate (H80R, D101N, D125H, E133ΔE, S134N and V148I) exhibit some of the characteristics of WT SOD1 (see Supplementary Material, Fig. S3).
Few address books out there today allow us to identify, aggregate and connect with all our many accounts.
We have adopted a similar approach to aggregate the individual biclusters identified from the bootstrap datasets.
The code generator needs to read the RM completely and to aggregate all data to identify how many files need to be generated.
In a next step, the raw scenarios identified are aggregated to a manageable number of scenarios by means of a cluster analysis.
All crops not identified were aggregated to the "others" census category which covers <6.8% of any of the country's total agricultural areas.
Additional interpretations have been identified at aggregate levels, like e.g. social groups, institutions, scientific communities or even countries citing each other.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com