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The F-MAN Consortium identified the requirements, designed the architecture, specified and developed the on-board and ground fixed components of an IT-based system enabling enhanced fleet management of freight railcars and introducing asset management in the process of the international transport chain.
As a result of a close collaboration between our bioinformatics group and experimental biologists, we have first identified the requirements for a pathway browser.
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Finance director Eifion Williams said: "The health board identified the requirement to deliver savings of £45m in 2012/13 to achieve a balanced financial position.
Under the Vision 2020 Plan, the Royal Bhutanese Government has identified the requirement for improved external air links by 2017, in an effort to increase tourism revenue 100% by 2012 and 150% by 2017.
As described above, our RNAi screen for glutamate receptors identified the requirement of dNR1 and dNR2 in PAM-α1.
If early stage disease is identified, the requirement for survival and life quality improvement will be met.
We have identified the requirement of TAK1 and IKK for hypoxia induced NF-κB in mammalian cells [ 24, 25].
Our additional experiments have identified the requirement of NEMO in regulating IL-8 and suggest that mutant p53 participates in this pathway.
We identified the requirement of PAP5 for maintaining basal defense responses against virulent Pst DC3000, suggesting a role for PAP5 in pathogen triggered immunity (PTI).
Recent studies have identified the requirement for HYLS-1, a gene that is associated with hydrolethalus syndrome, in apical targeting and anchoring of the centriole to the membrane (Dammermann et al., 2009).
Both our group and Pfizer aimed to find a simple way to introduce this trifluoromethylcyclopropyl unit, and the logical flow of our research program identified the requirement of synthesizing trifluoromethylcyclopropylsulfinate.
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