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Recent application of molecular genetics to this field has confirmed the crucial role of bioelectric signals in regenerative processes, identified the ion transporters responsible for generating instructive ion flows, and characterized downstream changes in gene expression.
A database search identified the ion as BSA peptide YIC*DNQDTISSK (residues 286 297).
We identified the ion channel ortholog genes KCNJ2, KCNJ12, KCNJ14, CACNA1S and SCN4A in the Felis catus genome, together with several polymorphic variants.
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From the scan in which the peptide is identified, the ions of the potential isotope cluster in previous and next scans are extracted from the raw data until the charges of both m/ z(O) and m/ z(O2) ions equal zero meaning there is not enough evidence to support the isotope cluster in that scan.
Combining the information of the ion energies and their velocities identifies the ion masses in the PPT plume.
David J. Julius, now Professor and Chair of the Dept. of Physiology at UCSF, is the recipient of the $1 million Run Run Shaw Foundation Prize in Life Science and Medicine (see attached press release) for his work identifying the ion channels involved in various aspects of nociception (pain perception).
The plot of Ca2+ + Mg2+ versus Na+ (Fig. 12b) was used to identify the ion exchange process.
The aggregated data was matched to reference chemical libraries to aid in identifying the ion set as a known metabolite or as a new unknown biochemical to be added to the library.
We report here our initial attempts to identify the ion channels that regulate the induction of the gene expression program associated with cardiac hypertrophy.
Among the genes involved in the immune protection through epithelial barrier function, we identify the ion transporter claudin-15 to be down-modulated early in the colon of Hnf4α mutants.
In this paper, the authors identify the ion channel kinase Trpm7 as a regulator of exocrine pancreatic development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com