Sentence examples for identified the binding of from inspiring English sources

Thus, two major pathogen-mediated entry mechanisms have been identified: the binding of bacterial adhesins to host cell receptors (zipper mechanism) and the injection of bacterial effector proteins into the host cell cytosol (trigger mechanism), both of which are followed by cell signaling pathways that result in cytoskeletal remodeling and subsequent engulfment [26].

Using the tools of virtual screening and NMR spectroscopy we identified the binding of two low-molecular weight fragments (2-aminobenzimidazole and indolin-2-one) to the 24 kDa N-terminal fragment of DNA gyrase B. Further in silico optimization of indolin-2-one led to the discovery of potent DNA gyrase inhibitors.

Similar to us, Marinov et al. not only identified the human mtDNA binding of c-Jun, Jun-D, and CEBPb but also identified the binding of five additional TFs.

Proteins bound to the beads were eluted by denaturing elution buffer, separated by SDS-PAGE and immunoblotted with antibodies against proapoptotic and antiapoptotic proteins to identify the binding of Bcl-2 family proteins.

While a full scale screen was not reported using this probe, the authors were able to identify the binding of the fragment N-phenylanthranilic acid to Lck.

MALDI-MS/MS was able to identify the binding of protein disulfide isomerase-related protein 5 (PDSIRP5) and peroxiredoxin 1/enhancer protein (PRX1/EP) to trivalent arsenic.

In our study, we identified the binding site of Elk-1 in regulating transcription of CIP2A by using series of CIP2A promoter-luciferase constructs.

Katoh et al. recently identified the binding domains of several key signaling effectors of the activin and WNT pathways on the promoter regions of CER in hESCs [ 32].

Docking calculations of the complexes of hDHFR with the most active compounds identified the binding mode of the described molecules with respect to MTX.

DROMPA accurately identified the binding sites of these proteins with a low false discovery rate (FDR) of <0.3% for almost all ChIP samples analyzed.

We then identified the binding region of noggin with BMP-2 and the receptors with BMP-2.