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In a historical prospective cohort study of people with CKD identified from electronic patient records, Gullion et al. identified that, compared to age and sex matched controls without CKD, people with CKD had higher levels of comorbidity and higher risk of mortality for the same degree of comorbidity [ 29].
Another dietary ingredient that interferes with absorption of sterols is soy protein, in which studies in animals and humans have identified that compared to casein, consumption of soy protein reduces intestinal absorption of cholesterol while enhancing fecal cholesterol excretion.
No large observational studies were identified that compared anti-VEGF drugs.
Two preclinical studies were identified that compared bevacizumab and the newer agent, aflibercept.
9 Of interest, research has identified that, compared with nothing, this practice can prevent HIV transmission, although in limited ways.
No studies were identified that compared an HA-coated tibial component to a cemented all-polyethylene tibial component.
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In addition, an ongoing trial was identified that compares transdermal oestrogen administered through patches with an LHRH analogue, but for which no outcome data are available (Abel, ongoing).
Only one cohort study [ 46] was identified that directly compared the risk of hip fracture between the classes of antipsychotics.
Methods An electronic search strategy with extensive MeSH headings was used in various databases to identify studies that compared bracing and non-bracing therapies.
Two genes, LOC_Os12g16540 and LOC_Os12g16720, were identified that were significantly down-regulated compared to wild type (see Additional file 1).
An ongoing Cochrane review has identified studies that compare trial protocols with subsequent publications (K Dwan, personal communication, 2010).
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CEO of Professional Science Editing for Scientists @ prosciediting.com