Since 2000, several sensitisation campaigns were conducted within communities, promoting dialogue, in collaboration with traditional and religious chiefs; female traditional practitioners and barbers were identified, sensitised and provided with new knowledge and skills.
For the purposes of this clinical research, the term pain sensitisation will be utilised, however, the lack of a widely accepted definition and criteria for identifying pain sensitisation is acknowledged as a limitation.
There is a need, therefore, to identify skin sensitisation hazard, and to assess accurately likely risks to human health.
A number of preclinical studies in other types of cancer have identified mechanisms underlying the sensitisation of cancer cells to TRAIL by bortezomib.
Finally, the biomarkers and sensitisation strategy identified in this study may not only prove to be effective in prostate tumours, but may be relevant to numerous cancer types as a mechanism for inherent radiation resistance.
With nitroimidazoles, definition of the relationship between one-electron reduction potential and the concentration required for a given degree of enhancement identified optimal physicochemical characteristics for radiation sensitisation (Adams et al, 1977).
In addition, PARP has been identified as a putative target for adjuvant sensitisation strategies.
Sensitisation to house dust mite, cat and mixed grass was assessed by skin prick tests with a positive response defined as a mean weal diameter of 2 mm or greater; this definition identified over 90% of participants sensitised to any one of a panel of up to 12 allergens.
Although HDACIs were recently shown to increase death induced by TRAIL in weakly TRAIL-sensitive tumour cells, the precise involved sensitisation mechanisms have not been fully identified.
17 Powdered latex gloves were identified as an important risk factor for latex sensitisation and allergy in HCWs as they were found to contain high allergenic protein content.
