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A coupled proton electron transfer (CPET) mechanism can be invoked to explain the major differences observed from the identified reactive intermediates in relation to the electrocatalytic activity of the electrode materials.
Based on the understanding of the embrittlement mechanism, some unique approaches for improving the intermediate-temperature ductility, strength and fabricability of Ni Ni3Si alloys were identified: reactive element doping (such as Zr and Y) to change the grain boundary chemistry; preoxidation to form adherent oxide layers; and thermomechanical processing to tailor the grain structure/shape.
However, all of these studies have focused on the stromal reaction of a particular tumor type, and although the identified reactive stromal gene expression signatures are reported to bear prognostic significance to the tumors they are associated with, it is unclear whether different tumor types share reactive stromal gene expression signatures or whether they elicit distinct responses.
Band 3 had the majority of reactive lysines on the large cytoplasmic N-terminal domain, whereas GLUT1 had all identified reactive lysines on the large cytoplasmic loop between TM6 and TM7 (Table 1).
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Schultz and colleagues (Schultz et al., 2007, 2009; Yarbrough and Schultz, 2007) used a combination of in chemico glutathione reactivity measures and in vivo LLNA data to identify reactive structural fragments within the subcategories of Michaels acceptors.
Finally, the research attempts to identify reactive intermediates in toxicant action to provide fundamental understanding of adverse toxicological effects from short-lived species implied in bioactivation reactions or environmental alteration processes.
The poor correlation between fractional solvent accessibility and thiol reactivity of the engineered hu4D5Fab variants indicated the value of PHESELECTOR biochemical assay to identify reactive thiol groups on the antibody-Fab surface.
In order to determine the progression of Purkinje cell loss, immunohistochemistry was performed on age matched mutant and control animals with anti-calbindin (CALB) antibody to label Purkinje cells and anti-GFAP antibody to identify reactive gliosis.
In previous studies, we found it possible to identify reactive CTL via the capture of lipophilic probes incorporated in the PM of APC expressing their cognate antigen [7], [9], [28].
In addition, the gating strategy used to identify reactive T cells had a major impact on assay outcome.
One major limitation of our study was that maternal and fetal cord bloods were not investigated to identify reactive oxygen species.
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