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To gain insight into the function of the GALA proteins we examined whether adaptation could have acted on a proportion of protein residues during the evolution of GALA LRRs and identified positions of such sites, using likelihood ratio tests (LRTs) and the Bayesian prediction [27], [28].
Using the previously identified positions of the various eIF3 subunits as a guide (Querol-Audi et al., 2013), we fitted the models to agree with features of the EM density.
Respondents identified positions of people they had discussed the CIS-2008 findings with at the P/T level, including Cabinet Ministers, senior staff (Deputies, Assistant Deputy Ministers, Communication Directors, provincial children's advocates), and policy analysts.
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(A) MCR-1 active site (P21 crystal form) with colours identifying positions of alanine substitutions.
Technologies exist to identify positions of metal surfaces and accumulation of ice, for example, despite outside conditions.
In essence, a highly m6A-specific antibody is used to immunoprecipitate methylated RNA fragments out of a randomly fragmented transcriptome; fragments are then deep sequenced to identify positions of signal enrichment.
To identify positions of chemically modified nucleotides in ERRE, primer extension analysis was used using 5 different oligonucleotide primers (Table 1), essentially as previously described in [43], [67].
Second, we find that, consistent with the eigenpositions, the corresponding 16S and 23S eigenorganisms identify positions of nucleotides that are approximately conserved within the respective taxonomic groups, but not among them.
Without any prior knowledge, we could identify positions of all known IS5 elements, and could determine a previously unknown insertion site with high sensitivity and specificity.
The second blue line shows information form the ppdb [ 19], and the database identify positions of REGs and a TATA box in the promoter.
The challenge of ab initio FS detection is, therefore, two fold: (i) to find a way to infer necessary model parameters and (ii) to identify positions of frameshifts (if any).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com