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His further research proposed new ideas about why atmospheric carbon dioxide was lower during ice ages, and he identified pathways that nutrients follow as they migrate from the Southern Ocean to seas farther north.
"Our study identified pathways that can be modulated in MS and we are working on tools for this.
By converging independent genomic datasets, we have identified pathways that have both biological function and genetic support to be important in PD.
Importantly, this activity was captured dynamically, which identified pathways that were initially activated by a biochemical stimulus, and those pathways whose activity was altered subsequent to the initial stimulus.
Pathway analyses for genes that were significantly different between the two groups were undertaken with the use of GenMapp software, and identified pathways that are frequently reported to be perturbed during carcinogenesis (Tables 2a and 3a).
Similarly to NBF, SNAL identified pathways that were associated with at least two of the phenotypes.
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Understanding the cellular signals that initiate the hypertrophic response is of critical importance in identifying pathways that mediate the hypertrophic heart's maladaptive deterioration to cardiac failure.
Current systems-based approaches focus on identifying pathways that may be used to subtype a disease and develop treatments for individual disease groups.
Understanding the cellular signals that initiate the hypertrophic response will be of critical importance to identify pathways that mediate the maladaptive deterioration of the hypertrophic heart to one of cardiac failure.
By unveiling the mechanisms by which the microbiota regulates fat storage, he says, the research helps identify pathways that are potential targets for antiobesity treatments.
It is therefore useful to identify pathways that are associated with tumor angiogenesis and the response to anti-angiogenic therapy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com