Data were collected by GCMS solution (Shimadzu), and identified metabolites are shown in Table 1.
Thirteen of the identified metabolites were significantly increased whereas seven were decreased.
Of the 398 identified metabolites, five metabolites were significantly lower during exacerbation compared to clinical stability.
Fig. 4 Cytoscape visualisation of 16 newly identified metabolites from the rice bran metabolome.
The processing mechanism of CW were discussed according to the identified metabolites.
The underlying regulations of EMGS-perturbed metabolic pathways were discussed according to the identified metabolites.
The identified metabolites belong to different phytochemical classes; polyphenolics, flavonoids, triterpenes and meroterpenoids.
A general comparison between the identified metabolites in roots and shoots revealed major differences between the two tissue types.
The reproducibility of the identified metabolites was assessed through examining formation patterns using different incubation times, substrate and enzyme concentrations.
To gain further insight into the biochemistry of identified metabolites, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were utilized.
Approximately 46% of total identified metabolites (209 metabolites) were classified as amino acids, cofactors & vitamins, and secondary metabolites and were interrogated for their potential human health-promoting properties.
