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Recent studies have identified matrix rigidity as a crucial regulator of TGFβ-induced EMT through several pathways [99, 118, 147, 156].
Similarly, we identified matrix metalloproteinase-2 (MMP-2) as a specific biomarker for pancreatic cancer, consistent with the experimental findings showing that its upregulation, compared with that of other metalloproteinases, seems particularly important in the growth and dissemination of pancreatic cancer [47] [49].
Gene ontology analysis identified matrix catabolic and metabolic pathway dysregulation.
In summary, we have identified matrix compliance as a new cell-type specific regulator of cytokinesis.
Sounni et al. identified matrix metalloproteinase-14 (MMP14) as the crucial protease that is activated downstream of type I collagen.
We recently identified matrix extracellular phosphoglycoprotein/osteoblast factor 45 (MEPE/OF45) as a new cofactor of CHK1 in rat cells.
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Inhibition of FAK blocked activation of the identified matrix-mediated pathways, while independent inhibition of JNK nearly abolished phosphorylated-c-Jun (p-c-Jun) and attenuated the pathways identified to promote enamel regeneration.
First, we identified matrices of the same length with the same IUPAC consensus sequence.
These mitochondrial phenotypes may be regulated by a newly identified matrix-localized isoform of MCL-1, associated with prevention of defective complex II enzymatic activity and disrupted supercomplex assembly.
The nucleotide distances between the different identified matrices of the most relevant models were then bound between minimal and maximal values.
Therefore, (V=I_n=[e_1,ldots,e_n]) is an (ntimes n) identify matrix.
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