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In those polyQ diseases where an NLS or NES has not been identified, localization of the protein has still proved to be important to pathogenesis.
Although further confirmation would be required in our samples for appropriate tissue and biological context, this analysis identified localization of diabetic DMPs to TFBSs of transcription factors that are known to regulate gene expression programs relevant to diabetes and wound healing, namely MAX, Sp1, and YY1.
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Therefore, we aimed to analyze the potential of diffusion tensor imaging (DTI) and consecutive cortical parcellation to identify localization of language.
In this study, we identified the localization of DMRT1 in adult testis.
We identified prominent localization of mucins in the pharynx of all four larval stages, in the adult hermaphrodite pharynx, vulva and anus, and in the tail of the adult male.
However, these stress fibres were rarely attached to FA as identified by localization of paxillin, a FA protein [ 16] and TNF-α did not induce a significant increase in the number of FA.
A Visual Basic macros embedded in the Access database was then used to pass each sequence through WoLF PSORT (located at http://wolfpsort.seq.cbrc.jp) to identify cellular localization of the protein; and the Signal P 3.0 server (www.cbs.dtu.dk/services/signalP/) to identify if the proteins are secreted.
In order to further identify the localization of C30F12.4 in germ cells and embryos, we isolated gonads and embryos and found that C30F12.4 was mainly located in the cytoplasm around the germ cells and everywhere in oocytes (Fig. 7C).
Because of the significant role of calcium signalling in plant responses to different environmental factors, calcium participation in LMF effects was investigated using a pyroantimonate method to identify the localization of free calcium ions.
With the use of fluorescently tagged versions of these markers or of antibodies to known markers, it becomes much simpler to identify the localization of a protein of interest.
We then docked the E. coli SecA (ecSecA-closed) [12], [13] and E. coli SecB X-ray crystal structures [14] into the EM density map to identify the localization of the molecules and domains in this complex (Figure 1D).
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