Sentence examples similar to identified its key role from inspiring English sources

The nuclear factor erythroid-2-related factor 2 (Nrf2, encoded by NFE2L2) pathway has been identified for its key role in mediating the cellular antioxidant protective response and thus as a potential candidate for targeted therapeutics in neurodegenerative disease.

Knowing how a polypeptide folds into a three-dimensional protein structure is key to identifying its role in disease and targeting drugs.

DOI: http://dx.doi.org/10.7554/eLife.01439.026 In addition to Rfx2, recent work has identified keys roles for the transcription factors Mcidas and Foxj1 in the development of MCCs (You et al., 2004; Stubbs et al., 2008, 2012).

The research findings confirmed the need to move beyond customary structural measures and identified the key role that urban planning can play in safeguarding urban water environments.

As a part of his MD/PhD training in the laboratories of Drs. Edward Wakeland and Chandra Mohan, he identified a key role for the CXCR4/SDF-1 axin in end-organ targeting, an important insight in the pathogenesis of SLE.

The study identified a key role played by NH4 + ion in the directional growth of the micro-tube structure.

This is a newly identified and key role for Wg in the presumptive notum.

Our group subsequently identified a key role for JNK in this process.

Using Enpp1 −/− mice we identified a key role for NPP1 in maintaining the size of osteocyte lacunae.

For example, we demonstrate that parsing GWAS gene lists into functional groups identified a key role for oxidative phosphorylation, which can now be experimentally validated.

The Pdgfrb-Cre strategy identified a key role for myofibroblast αv integrins in regulating fibrosis in several solid organs, including liver, lung, and kidney.