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Curiously both folds have been identified in structures of retaining and inverting transferases, indicating that the fold-family does not dictate the mechanism (for a recent review see [7]).
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This subpopulation corresponds to subpopulation 1 (SO, YS and RC) as identified in STRUCTURE (Figure 1A).
The materials identified in Structure 1 are used commonly enough to provide some comparison across multiple studies and multiple laboratories.
Within populations, we tested for associations between microsatellite genotypes and Bd susceptibility using STRuctured population Association Test (STRAT) (Pritchard et al. 2000b) to examine disease associations independently for each genetic deme identified in STRUCTURE (Pritchard et al. 2000a).
Notably, the substrate-binding channel identified in these structures is different from that inferred for previous structures containing fatty acids.
In Es. coli DHFR, this Met20 loop was identified in crystal structures to form an open, occluded, and closed structure.
The largest regions with overactivation were identified in subcortical structures (bilateral thalamus, bilateral caudate, left putamen, pallidum, and amygdala).
Population coding has been identified in many structures, including the retina [7], motor cortex [33], and hippocampus [34].
These singularities may be identified in soluble structures by determining the number of side-chain nonpolar groups –the so-called wrappers- contained within the bond local environment (Methods).
Most components of the local RAS have already been widely identified in eye structures [ 10, 21].
Five Ca2+-binding sites, none of which adopt an EF-hand motif, were identified in the structure of a Ca2+-bound inactive mutant with and without bound substrate.
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