Sentence examples for identified in large from inspiring English sources

Alternatively, spliced transcripts have been experimentally identified in large numbers through de novo sequencing methods such as conventional expressed sequence tag (EST) sequencing and massively parallel signature sequencing [17, 20, 21, 25].

There have been few studies on genetic sequence variants in sporadic MSA [9] [20] and no environmental risk factors have been consistently identified in large samples.

However, the eyeless alternative splicing event was not identified in large scale analysis of alternatively spliced pre-mRNAs that are aberrantly regulated in B52-deficient tissue culture cells [54].

The problem of off-target-effects (OTEs) has raised some concern over previously published results, and highlighted the importance of thorough validation of candidates identified in large scale RNAi screens through a variety of techniques [8], [9].

We applied kriging, a geo-statistical technique, to explore the spatial and temporal spread of influenza and found that, during 2008, influenza was first identified in large port cities and then gradually spread to other parts of the country.

We fully appreciate that our sample size is moderate but we believe that to a large extent this is, at present, inevitable, as ANK3 is not a gene that was theoretically predicted as being of relevance to BD. Thirdly, the risk conferring allele is exceedingly rare and was therefore only identified in large samples pooled from different studies.

Furthermore, the biological roles of many of the genes identified in large-scale expression studies are not well characterized and do not link genes to specific regulatory pathways since the expression profile can be a direct or indirect result of the treatments.

PALD (KIAA1274) was identified in large-scale cDNA sequencing efforts [13].

These sites correspond to phospho-sites identified in large-scale phospho-proteome analyses [18], [19], [20].

Its retina is cone dominant and a number of disease models of impaired vision exist in larval zebrafish [4], [5], most of which were identified in large-scale mutagenesis screens.

But considering these SNPs were originally identified in large-scale genome-wide association studies and all the traits analyzed were highly related, the impact of multiple comparisons may be limited.