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LTTRs with the ability to oligomerize as λ cI repressor fusions were initially identified in a large scale screen of the E. coli genome [20].
TMEM9B was also identified in a large scale study to identify genes activating NF-κB and MAPK signalling pathways [ 18].
These two mutants were identified in a large scale screening of EMS-induced mutant deficient in Rh1 expression.
Furthermore, a direct interaction of hornerin with PinX1 was identified in a large scale mapping of protein-protein interactions by mass spectrometry [ 42].
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SNP rs17782313 had been identified in a large-scale international cooperation encompassing more than 90,000 individuals [1].
Bulldog mutations were identified in a large-scale mutagenesis screen for embryonic lethal mutations disrupting craniofacial cartilage development [13].
Recently, CD97 was identified in a large-scale genome RNAi screening as one of six uncharacterized host factors that are required for HIV replication [45] suggesting its crucial post-integration role.
The strongest validation of Tat-SF1's role in the HIV-1 lifecycle was revealed when it was identified in a large-scale, RNAi-based screen for HIV-dependency factors (HDFs) [37].
Additionally, four new GLI antagonists have been identified in a large-scale, high-throughput screening by Hyman and collaborators [ 95].
Our genome-wide investigation was based on the peak TSS positions in promoters that had been identified in a large-scale experimental analysis.
The mutations with a PSG phenotype were identified in a large-scale EMS-mutagenesis screen on the third chromosome (Wang et al. 2008).
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CEO of Professional Science Editing for Scientists @ prosciediting.com