Sentence examples for identified hit from inspiring English sources

The identified hit fragments had promising structural diversity.

We then decided on a gain of 400 per identified hit.

In silico and in vitro screening of our compound collection has identified Hit 2 as BRAFV600E inhibitor.

In silico and in vitro screening of our designed pyrazole derivatives has identified Hit 1 as BRAFV600E inhibitor.

Based on the newly identified hit compound 17a, three series of compounds were synthesized and evaluated for both HDAC1 inhibitory activity and cytotoxicity.

We synthesized a series of 1,2,3,4-tetrahydroisoquinoline-type 1,2,3,4-tetrahydroisoquinoline-type 1,2,3,4-tetrahydroisoquinoline-typeg to impositivee metallostericbility of the previously identified hit comodulatorsAM-3 (2).

Enzyme assay for these compounds identified hits with micro molar activity.

Herein, we report the biological evaluation of recently identified hits from pharmacophore based virtual screening.

The identified hits were validated using molecular docking and molecular dynamics simulation studies.

The results obtained in this study gave assurance about the identified hits as prospective inhibitors of MbtI.

Thus, these identified hits show good binding affinities with WT and mutant ROS-1 proteins that may be further evaluated for their in-vitro/in-vivo activity.