Exact(1)
Using high-throughput sequencing of mutagenized alleles, we identified guide sequences that correlate with sgRNA mutagenesis activity and used this information for the rational design of all possible sgRNAs targeting the Ciona transcriptome.
Similar(59)
These were manually identified, guided whenever possible by ESTs available via BLAST searching [ 18].
With increasing miRNA data, it is desirable to design methods to identify guide strand based on machine learning algorithms.
Drawing on industry interviews, six interconnected socio-technical factors are identified that guide the vehicle design and manufacturing process.
To analyze and monitor molecular content in specific cellular compartments, different parts of cellular architecture must be unambiguously identified to guide Raman image/spectra acquisition.
Then optimum operational conditions have also been identified to guide the optimal design of the proposed wall and the application of solar energy in buildings.
Risk behaviors related to the socioeconomic context could be identified to guide specific interventions.
Chemoresistance, anti-apoptosis and EMT genes identified may guide us to potential molecular targets.
Where co-factors/co-enzymes have been identified, the Guide indicates their involvement.
Competing pathways that might prevent the achievement of this theoretical maximum were identified to guide future genetic studies.
Although poor prognostic features for JE have been identified, and guide management, relatively little is reported on the remaining three-quarters of AES cases.
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