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How is the 'diversity' of a compound set defined and how is the most appropriate compound subset identified for assay when screening the entire HTS deck is not an option?
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These relationships were identified for assaying the amount of CEAs.
A list of detected microRNAs in each sample and the differentially expressed microRNAs between two samples were identified for each assay.
This review will not focus on artifacts that have been identified for toxicological assays related to human health end points or for nanomedicine (interested readers should see, for example, this review article), but insights drawn from these studies concerning artifacts and misinterpretations relevant to ecotoxicological testing will be highlighted.
The BAC clones which were identified for the different assays were analyzed with the help of gene-specific amplicons (Additional file 4) for the presence of the different Brassica napus loci.
Future detailed examination of the precise analyte we identified for our CO4-MMP assay may shed more light on the processes leading not only to tissue degradation but also to tissue formation.
Optimal antibody concentrations were identified for each lysate and FFPE assay as follows: Each antibody in each assay was titrated both independently and dependently to assure saturation of epitope in high-expressing samples.
Half-maximal activity concentrations (AC50) were identified for 729 chemicals in 256 assays (7,135 chemical assay pairs).
In this study, using genome-wide profiling of breast tumours from multiple cohorts as well as validation by cell-based phenotypic assays, we identified for the first time that SPINK1 is a biological driver of aggressiveness in breast cancer.
To determine if the binding site identified for FruMB was correct, a modified assay was performed in test tubes.
Clinically relevant cut-off levels should be identified for specific groups of patients and assays, and prospectively validated for their predictive value over the development of clinical symptoms of infection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com