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Furthermore, druggability of each of the identified drug targets was also evaluated by the DrugBank database.
The identified drug targets could be useful for an effective drug discovery phase.
Brindha et al. [18, 19] identified drug candidates against Mtb MurE and PknB using docking based virtual screening method.
The identified drug was included in the treatment protocol of the patient and its concentration was monitored in the liquor.
For companies, the payoff will come later, when they develop compounds to block the newly identified drug targets.
To document drug therapy problems and their causes and assess pharmacist follow-up of patients with identified drug therapy problems.
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In this study, by relating pharmacological space with genomic space on the basis of the PPI network, drugCIPHER successfully identified drug-target interactions and predicted biological fingerprints in silico for 726 FDA approved drugs.
We selected genes with expression patterns representative for the identified drug-responsive transcriptional networks.
Firstly, we identified drug-perturbed pathways using the SubpathwayMiner software package [ 18] (see Figure 1).
The depression guideline did not discuss any of the identified drug-disease interactions.
In addition to the disease-metabolite associations, we also identified drug-associated metabolites.
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