Relative to the use of a single HMM for the family as a whole, subfamily HMMs have improved sensitivity at the same false positive rate: they identify dramatically more true positives under high significance cutoffs and provide greater separation between true and false positives.
But drawing on controversies over economic stimulus, bailouts and health legislation, he identified a dramatically different set of villains.
Although the number of insertions identified was dramatically reduced, we saw the same pattern of differential TE abundance, in particular fewer TEs in C. orientalis (Additional file 2: Figure S2b, generalized linear model with Poisson distribution, z = −9.394, p < 0.00001).
In total, eight pairing events TRBV6-6 with TRBJ1-5, TRBV15 with TRBJ1-2, TRBV3-1 with TRBJ2-3, TRBV24-1 with TRBJ1-4, TRBV15 with TRBJ2-7, TRBV29-1 with TRBJ1-6, TRBV7-9 with TRBJ1-5, and TRBV4-2 with TRBJ2-2 were identified as dramatically increased in either one of the malignant samples.
A total of 1428 acetylated proteins with 3163 unique modification sites were identified, which is dramatically higher than those in other previously reported microorganisms (Table 1).
The number of pairs identified
(6000 Mr), cysteine-rich proteins, was identified as being dramatically induced by hypoxia in human adipocytes.
Finally, using a genetic approach, we identified new genes dramatically upregulated in cells resistant to ferroptosis.
Clusters, or groups, of coexpressed genes were identified that showed dramatically different expression levels across the tumor cohort tested.
Sizes of the identified duplicons vary dramatically, ranging from one to 26 genes, or from 234 bp to 108 Kb in size.
