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Candidate predictors differed substantially across the identified derivation studies (Table 2), and after variable selection a median of 5 included predictors was found (range 2 12).
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Two reviewers independently screened the titles and the abstracts of all retrieved references to identify derivation studies of prognostic instruments.
Here we employ phylogenetic hypotheses to identify the derivation of species from Andean or Amazonian ancestors, focusing on modern clades of rodents of the family Echimyidae (Caviomorpha: Octodontoidea) that are co-distributed among these regions.
This approach of identifying a derivation cohort and then prospectively testing the resulting model developed is a much more rigorous approach than simply defining and using the model without a confirmatory cohort.
We use these tests to identify which derivation dataset(s) are strongly correlated (p-value ≤ 0.001) with the validation dataset with regard to readmissions, as such correlation provides an initial indication of which derivation dataset(s) may serve as good candidate(s) for developing the final models.
The best performing BMI cut-off points identified using the derivation cohort data were considered for inclusion in the decision protocol (table 4).
The three best performing decision rules identified using the derivation cohort data were considered for inclusion in the decision protocol (table 3).
However, we were only able to validate the most pronounced transcriptional changes identified in the derivation cohort.
Using the variables and their respective weightings identified in the derivation cohort (table 2), individual risk of AHFS was predicted.
The OSA predictors were identified on a derivation population and used to develop the diagnostic algorithm, which was validated on an independent population.
Nineteen significant procedures were identified from the derivation cohort with points ranging from −3 to 23, producing a severity index with possible range of −13 to 69.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com