We then used an automated algorithm to identify cut off points where the cumulative density of photons from the highest elevation indicates the presence of the canopy top and likewise where such cumulative density from the lowest elevation indicates the mean terrain elevation.
The log-linear relationship identified cut-offs of <25%, 25 60% and >60% parasite prevalence in children <5 years of age to be approximately concordant with the low, medium and high transmission intensity using EIR [25].
All data will be dichotomised across identified cut-off values.
In addition, we took an unbiased approach, specified no categories, and identified cut-off levels based on the data by employing classification and regression analysis (CART).
Recently, a monocentric study identified cut-off values for mean platelet volume (MPV) and mean platelet diameter (MPD) with good diagnostic accuracy in this respect.
The previously identified cut-off value for MPV had 91% specificity in distinguishing ITP from inherited macrothrombocytopenias (mono and biallelic Bernard-Soulier, MYH9-related disease), while its sensitivity was greatly variable depending on the instrument used.
It also plans to make immediate improvements in nurse staffing in health facilities falling below an identified cut-off point (a WISN ratio of 0.6 or less, meaning 60% or less of required staffing).
The McNemar test was used to compare the incidence of LBW using the traditional cut-off (2500 g) to that yielded by our newly identified cut-off, and the agreement between the two was also computed.
The identified cut-off point for PASS may easily be incorporated as endpoints in clinical trials and will provide information about the proportion of patients achieving acceptable state of symptoms.
Using CRT analysis we have identified cut-off limits for early clinical parameters of uncontrolled sepsis, like WBC, blood glucose and platelet count, allowing, when combined with GA and BW data, capture of 75% of treatment failure cases with a specificity of 89% within 24 h.
To allow comparison across variables, sensitivity and specificity analyses identified cut-off values for preferred outcome, and relative risks for being above or below cut-offs were calculated, as was the 'proportion of treatment effect explained' (PTEE) to identify biomarkers that contribute to benefit from DrotAA.
