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If the targets identified can lead to means of increasing HbF to therapeutic levels in sufficient numbers of sickle or β-thalassemia erythrocytes, the pathophysiology of these diseases would be reversed.
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When such a change is identified, it can lead to identifying modifier loci that modulate phenotypes, as has recently been done in models for Rett syndrome (Buchovecky et al., 2013; Grillo et al., 2013), leading to a better understanding of pathophysiology and opportunities for therapeutics.
A number of mechanisms have been identified that can lead to (acute) aquatic toxicity.
By analyzing the changes in resistances the limitations in an MEC can be identified which can lead to improved cell design and higher hydrogen production rates.
Various agents and mechanisms have been identified which can lead to a quantitative or qualitative deficit in pancre atic B-cells.
On the government website for the animal, they are listed as being under "special concern"—meaning that they are not currently threatened but "a combination of biological characteristics and identified threats" can lead to them being endangered.
A variety of constellations of human errors and/or equipment failure have been identified, that can lead to harmful incidents during patient transfer [ 12– 12].
Leaf biomass characteristic QTLs [ 236, 245- 247] have also been identified which can lead to increased biomass as well as increased crop density resulting in greater yields.
When molecular genotyping technology is applied to outbreaks or unusual clusters of disease, persons sharing M. tuberculosis strains can be identified, which can lead to important clues about the pattern and dynamics of transmission.
By including a 'global' measure of social support, specific sources of social support will not be identified, which can lead to misconceptions of the primary correlates and possibly biased results.
Conversations with students to determine the reason behind concerns identified in assignments can lead to a greater understanding of student approaches and great discussions about academic integrity and its links to personal integrity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com