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Cellular transforming genes (c-onc) are evolutionarily conserved vertebrate DNA segments which have been identified by two different approaches.
In some cases, the TFBS was independently identified by two different tools/databases (e.g. PBX-1 binding site in upstream region; table 2).
Significantly expressed genes (a fold change of >2.0) were identified by two different; Benjamini-Hochberg multiple testing correction-ANOVA-test (α = 0.05) [65], and the two-class unpaired algorithm from the Significance Analysis of Microarrays package (SAM, http://www-stat.stanford.edu/~tibs/SAM/).edu/~tibs/SAM/
Interestingly, miR-219, despite being independently identified by two different groups as a key regulator of oligodendrocyte differentiation and CNS myelination [11], [12], was not identified as being differentially expressed in Dicerfl/fl Dhh-Cre+ peripheral nerves in our miRNA screen.
Repeat sequences were identified by two different methods.
The numbers of proteins specifically identified by two different digestions was 571, accounting for 56% of the 1026 identified proteins.
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A pipe is identified by three different size categories: nominal pipe size, outside diameter, and inside diameter.
Two H-2d restricted CD4+ T epitopes, N60 (S435–444) and P152 (S1111–1127), and two H-2d restricted CD8+ T cell epitopes, N50 (S365–374) and P141 (S1031–1047) were identified by three different methods, enzyme-linked immunosorbent assay (ELISA), enzyme linked immunospot assay (ELISPOT) and fluorescence activated cell sorter (FACS).
KLK6 was initially identified by three different groups, naming it zyme in Alzheimer's disease [ 29], protease M in breast cancer [ 30], and neurosin in colon adenocarcinoma [ 31].
We compared the recurrent regions identified by three different methods: GISTIC2, GAIA and RAIG, running each of the first four methods with their default settings and selecting predictions with q-value < 0.5.
One hundred thirty-four incident RA cases identified by four different local and national registers, who had participated in a community-based health survey between 1991 and 1996, were included.
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