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For each received packet (identified by the classical 5tuple composed of the source and destination addresses, the source and destination port numbers together with the protocol type), only the destination port will be considered and hashed into a random value.
Spacers that were wrongly identified by the classical spoligotyping varied among centers.
Furthermore, we consider only the true positive identified couples in excess of those identified by the classical methods.
The hierarchical model confirmed that 3 centres identified by the classical approach as low outliers performed better than the mean.
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Only the 2009 H1N1 outbreak and Thai strains described above were identified by the exhaustive search as classical-Eurasian reassortants.
This did not overlap with any of the areas identified by the free > instructed contrast in the classical context.
This analysis was done within each of the ROIs identified by the free > instructed contrast in the classical context (see Fig. 4 and Table 2).
On the contrary, 4 centres among the high outliers identified by the hierarchical model were found to perform not differently from the mean using the classical model.
These domains were identified by the program Phobius that was specifically designed to distinguish between N-terminal transmembrane domains (TMs) and "classical" type II secretion signal sequences [ 23].
In order to minimize the risk of false-positive results, only the parameters identified by both classical statistics and SAM analysis were considered as significant.
Comparing our methodology with the commonly used general supervised inferential approach (with statistical test such as SAM) we were able to better characterized different physiopathological aspects of AF, aspects impossible to be separately identified by a classical supervised approach [12].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com