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About two-third of the metabolites that we identified as responsive to drought and associated with tolerance were unknowns (Fig. 5).
It is possible that multi-unit recordings are limited in their sensitivity as a particularly responsive neuron can cause an entire cluster to be identified as responsive when the majority of units are unresponsive.
Two groups display a nuclear Arc signal which can be clearly identified as responsive to shock-US delivery: the DS and LI groups (group main effects: F3,12 = 37.40, P<.001; P's<.01 for DS/LI vs. control, Tukey's HSD).
Interestingly, genes identified as responsive to sex chromosome complement in mammals were enriched for candidates sensitive to HP1 [ 60].
Lipid, fatty acid, and bile acid metabolism pathways were identified as responsive to CR in mouse serum by these authors.
Based on the above-mentioned classification, a total of 230 patients (53%) were identified as responsive, with 5- and 10-year RFS rates of 90.4 and 86.0% respectively.
Similar(43)
However, genes identified as As responsive are in part related to a general stress response resulting from the toxic effects of As and are unlikely to play a significant role in As tolerance.
Since it is difficult to distinguish between the effects of light and metabolic stimulus [ 71, 72], it is possible that elements identified as light responsive might be metabolite responsive instead.
Several CsNAC genes, including CsNAC35, which is an orthologue of the known stress-responsive Arabidopsis RD26, were identified as highly responsive to abiotic stresses and hormones.
These contigs define a core set of low-temperature responsive genes from barley, including genes previously identified as cold responsive, such DHN5 [43], that are likely to play critical roles in cold acclimation (HVSMEa0006I22r2_s_at and contig1717_s_at) (Table S10).
The Arabidopsis RESPONSIVE TO DEHYDRATION 26 (RD26) cDNA was first identified as dehydration responsive gene that was later shown to encode a NAC TF and functions in a novel abscisic acid (ABA -dependent stress-signABA -dependent.
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